Journal: Antibiotics (Basel, Switzerland)
Article Title: Design and Synthesis of Novel Amino and Acetamidoaurones with Antimicrobial Activities.
doi: 10.3390/antibiotics13040300
Figure Lengend Snippet: Figure 4. Evaluation of the toxicity of compounds 10, 12, 15, 16, and 20 on human cells. Human cells corresponding to kidney epithelial cells (A498), lung epithelial cells (BEAS-2B), intestinal epithelial cells (Caco-2), skin cells (HaCaT), liver cells (HepG2), or fibroblasts (IMR-90) were exposed to increasing concentrations of aurones for 48 h before measurement of the cell viability using resazurin. Results are expressed as % of cell viability, DMSO alone being used as negative control giving 100% viability. Data were plotted using GraphPad Prism 7 (means +/−S.D, n = 3).
Article Snippet: Human cells used were kidney epithelial cell line A498 (ATCC® HTB-44), normal lung epithelial cells BEAS-2B (ATCC® CRL-9609), intestinal cell line Caco-2 (ATCC® HTB-37), normal epidermal keratinocytes (HaCaT) (from Creative Bioarray, Shirley, NY, USA), liver cell line HepG2 (ATCC® HB-8065), and normal lung fibroblasts IMR-90 (ATCC® CCL186).
Techniques: Negative Control